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Gold Colloid
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Image Search Results
Journal: Nanoscale Research Letters
Article Title: T cells enhance gold nanoparticle delivery to tumors in vivo
doi: 10.1186/1556-276X-6-283
Figure Lengend Snippet: Biodistribution comparison of AuNPs and AuNP-T cells in mice . Mice were injected with PEG-AuNPs (60-65 nm hydrodynamic diameter), AuNP-T cells, or PBS and subsequently sacrificed at various time points to determine biodistribution. PBS gold levels were negligible in comparison to AuNP and AuNP-T cell groups for all organs. Values are percentage of the injected gold dose (%ID) were calculated from ICP-MS and are normalized for dry weight differences. The AuNP-T cell group exhibited significantly higher gold delivery to the lungs, liver, and bone, while the AuNP group demonstrated higher gold levels within the small intestine. No significant differences were seen in the spleen, kidney, muscle, or brain. An asterisk indicates statistically significant ( P < 0.05) differences.
Article Snippet: We next performed a comprehensive in vivo biodistribution study using inductively coupled plasma mass spectrometry (ICP-MS) and ICP-OES to map the location of free PEGylated
Techniques: Comparison, Injection
Journal: Nanoscale Research Letters
Article Title: T cells enhance gold nanoparticle delivery to tumors in vivo
doi: 10.1186/1556-276X-6-283
Figure Lengend Snippet: AuNP-T cells enhance the delivery of gold nanoparticles to the tumor site in vivo . Tumor-bearing mice were injected i.v. with PEG-AuNPs or AuNP-T cells. Tumors were subsequently resected at various time points and measured for AuNP content using ICP-MS. Values displayed represent the percentage of injected gold normalized for tumor dry weight differences (mean ± SEM). The percentage of gold delivered by the AuNP-T cells at 48 h represents a significant, four-fold increase over the PEG-AuNP group at 24 h ( P < 0.01).
Article Snippet: We next performed a comprehensive in vivo biodistribution study using inductively coupled plasma mass spectrometry (ICP-MS) and ICP-OES to map the location of free PEGylated
Techniques: In Vivo, Injection